HPK1-IN-52 is a potent and orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 value of 10.4 nM. HPK1-IN-52 exhibits anti-tumor activities.

Product information

CAS Number: 2994298-66-5

Molecular Weight: 556.61

Formula: C31H30F2N6O2

Smiles: O=C1NC=CC2=C1C(=CC=C2C1=CN=C2C=C(F)C=CN12)NC1=CC=C(C2CCOCC2)C(CN2C[C@@H](F)CC2)=N1

InChiKey: FHMXXBCVBMXMSE-NRFANRHFSA-N

InChi: InChI=1S/C31H30F2N6O2/c32-20-7-12-39-27(16-35-29(39)15-20)23-1-3-25(30-24(23)5-10-34-31(30)40)36-28-4-2-22(19-8-13-41-14-9-19)26(37-28)18-38-11-6-21(33)17-38/h1-5,7,10,12,15-16,19,21H,6,8-9,11,13-14,17-18H2,(H,34,40)(H,36,37)/t21-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.